5-MeO-DMT (whose full name is 5-Methoxy-N,N-Dimethyltryptamine) is a psychedelic found in many plants and animals, including its most well-known source, the toad known both as the Sonoran Desert Toad and the Colorado River Toad (Bufo alvarius/Incilius alvarius). 

5-MeO-DMT is extracted from the parotid glands of the toad, though it can also be synthetically synthesized in a laboratory as well. 

It is distinctly different from DMT in its effects and is widely regarded to be a more intense experience. Those who have experienced 5-MeO-DMT have reported intense emotions, a feeling of oneness with the universe, ego dissolution and perspective shifts.

5-MeO-DMT is currently legal in Canada and Mexico.