Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis
Multiple sclerosis (MS) is a debilitating neurodegenerative disease characterized by demyelination and neuronal loss. Traditional therapies often fail…
Subjective ibogaine experiences across intersecting social-ecological dimensions
Background and aims
Ibogaine, an alkaloid extracted from the root of the Tabernanthe Iboga shrub, holds promise in treating addictive disorders. In…
Ibogaine – A legacy within the current renaissance of psychedelic therapy
Ibogaine is a powerful psychoactive substance that not only alters perception, mood and affect, but also stops addictive behaviors. Ibogaine has a ver…
Psychedelic treatment for co-occurring alcohol misuse and post-traumatic stress symptoms among United States Special Operations Forces Veterans
Background & aims
Special Operations Forces Veterans (SOFV) have unique treatment needs stemming from multiple repeated forms of combat exposure resul…
Prospective associations of psychedelic treatment for co-occurring alcohol misuse and posttraumatic stress symptoms among United States Special Operations Forces Veterans
This study evaluated prospective associations of ibogaine and 5-MeO-DMT treatment for risky alcohol use and post-traumatic stress disorder (PTSD) symp…
Psychedelic Treatment for Trauma-Related Psychological and Cognitive Impairment Among US Special Operations Forces Veterans
Background
U.S. Special Operations Forces Veterans are at increased risk for a variety of mental health problems and cognitive impairment associated w…
Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes
Methods: In this observational study, 30 subjects with DSM-IV Opioid Dependence (25 males, 5 females) received a mean total dose of 1,540 ± 920 mg ibo…
A Single Administration of the Atypical Psychedelic Ibogaine or Its Metabolite Noribogaine Induces an Antidepressant-Like Effect in Rats
Abstract
Anecdotal reports and open-label case studies in humans indicated that the psychedelic alkaloid ibogaine exerts profound antiaddictive effect…
Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes
Background
Ibogaine may be effective for transitioning opioid and cocaine dependent individuals to sobriety. American and European self-help groups pr…
Safety of ibogaine administration in detoxification of opioid dependent individuals: a descriptive open-label observational study
Background
Ibogaine is an indole alkaloid used in rituals of the Bwiti tribes of Africa. It is also used in non-medical settings to treat addiction. H…