Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness
Background
Recent years have seen a resurgence of research on the potential of psychedelic substances to treat addictive and mood disorders. Historica…
5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics
Serotonin (5-hydroxytryptamine; 5-HT) 2A receptor (5-HT2AR) signaling is essential for the actions of classical psychedelic drugs. In this study, we e…
Serotonin toxicity of serotonergic psychedelics
Rationale
In recent years, psychedelic substances with serotonergic mechanisms have accumulated substantial evidence that they may provide therapeutic…
Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample
Background:
Over the last two decades, a number of studies have highlighted the potential of psychedelic therapy. However, questions remain to what ex…
Increases in Psychological Flexibility Mediate Relationship Between Acute Psychedelic Effects and Decreases in Racial Trauma Symptoms Among People of Color
Background
Previous research showed acute psychedelic effects were associated with decreases in racial trauma (RT) symptoms among black, indigenous, a…
Prevalence and associations of classic psychedelic-related seizures in a population-based sample
Objectives
Previous studies have reported links between classic psychedelic use and seizures, but little remains known about prevalence and potential …
Exploring the case for research on incorporating psychedelics within interventions for borderline personality disorder
Borderline Personality Disorder (BPD) is a severe psychiatric disorder characterized by behavioral dysregulation, emotion dysregulation, disturbances …
Integrating psychotherapy and psychopharmacology: psychedelic-assisted psychotherapy and other combined treatments
Introduction
Combinations of psychotherapy with antidepressants are gold-standard psychiatric treatments. They operate through complex and interaction…
Psychedelic-Inspired Approaches for Treating Neurodegenerative Disorders
Psychedelics are increasingly being recognized for their potential to treat a wide range of brain disorders including depression, post-traumatic stres…
The emerging science of microdosing: A systematic review of research on low dose psychedelics (1955 – 2021)
The use of low doses of psychedelic substances (microdosing) is attracting increasing interest. This systematic review summarises all empirical microd…